Maybe this is a dumb question, but why? If you were building an aircraft like this from scratch, why design it to require a present human pilot? Satellite latency too long?
Sure but "earlier in the process"? SpaceX is trying to become passenger-safe as well, they just have the luxury of being able to sell something human-less in the meantime.
As far as I know the cost for going supersonic is extremely high compared to subsonic. There probably isn't much cargo that really needs to be there a few hours earlier. Even the military doesn't have supersonic cargo planes. All (most?) bombers are subsonic too.
The military has used supersonic aircraft on cargo missions in exceptional cases, actually. Their supersonic aircraft tend to be vastly less efficient than even Concorde, though.
The only long range strategic bomber developed after the 50s that wasn't supersonic was the B-2 stealth bomber (not that there have been very many strategic bombers developed after the 50s).