I use it primarily with ExtJS and backbone. What I've done with mozrepl is inject some global javascript, then call methods off it over the network link, so for instance I have a reloadModel method that will remove the model's definition (basically delete window.Foo, but a bit more to it), then reload's the JS file which re-creates it. I've got this bound to occur automatically with emacs when coffeescript/js files save.

This method works for anything that can be removed from a system then reloaded. I'm not sure you could do that with jQuery, but you might be able to with a plugin I suppose. No idea on dojo, sorry.

My fixes for the nightlies is at: https://github.com/nathanstitt/mozrepl I haven't submitted a pull request until I'm sure things have settled down with the Firefox changes, but plan to do so soon.

Hit me up if you want further details.