This gets proposed from time to time (was Buckminster Fuller's Dynaxion Home the first?), but I can never see how you'd move them without crating up all your possessions. And isn't that the worst aspect of moving home in a traditional manner...?
If the home is deliberately designed for this possibility, it might be easier than that. For instance, perhaps a grid of plugs to bolt your furniture into so that you only have to crate up looser items like books and vases? And you might be able to hide those under floorboard panels.
I've had a couple of relatives move mobile homes[1] and mostly it can down to boxing the dishes, taking the knick knacks off the wall, and tying the furniture together[2]. I'm more interested in the mass production aspect.
